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Application of Recombination -Induced Tag Exchange (RITE) to study histone dynamics in human cells

In eukaryotes, nucleosomes form a barrier to DNA templated reactions and must be dynamically disrupted to provide access to the genome. During nucleosome (re)assembly, histones can be replaced by new histones, erasing post-translational modifications. Measuring histone turnover in mammalian cells ha...

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Detalles Bibliográficos
Autores principales: Molenaar, Thom M., Pagès-Gallego, Marc, Meyn, Vanessa, van Leeuwen, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518693/
https://www.ncbi.nlm.nih.gov/pubmed/32228348
http://dx.doi.org/10.1080/15592294.2020.1741777