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Application of Recombination -Induced Tag Exchange (RITE) to study histone dynamics in human cells
In eukaryotes, nucleosomes form a barrier to DNA templated reactions and must be dynamically disrupted to provide access to the genome. During nucleosome (re)assembly, histones can be replaced by new histones, erasing post-translational modifications. Measuring histone turnover in mammalian cells ha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518693/ https://www.ncbi.nlm.nih.gov/pubmed/32228348 http://dx.doi.org/10.1080/15592294.2020.1741777 |