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Different post-mortem brain regions from three Chinese FFI patients induce different reactive profiles both in the first and second generation RT-QuIC assays

Fatal Familial Insomnia (FFI) is one of the most popular genetic prion disease (gPrD) in China. Unlike the other types of human prion diseases, FFI patients show distinctive neuropathological characteristics, such as less deposition of PrP(Sc), low tissue infectivity and severe neuron losses in some...

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Detalles Bibliográficos
Autores principales: Xiao, Kang, Shi, Qi, Zhou, Wei, Dong, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518747/
https://www.ncbi.nlm.nih.gov/pubmed/32573356
http://dx.doi.org/10.1080/19336896.2020.1782809