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Methionine oxidation within the prion protein

Prion diseases are characterized by the self-templated misfolding of the cellular prion protein (PrP(C)) into infectious aggregates (PrP(Sc)). The detailed molecular basis of the misfolding and aggregation of PrP(C) remains incompletely understood. It is believed that the transient misfolding of PrP...

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Detalles Bibliográficos
Autores principales: Bettinger, John, Ghaemmaghami, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518762/
https://www.ncbi.nlm.nih.gov/pubmed/32744136
http://dx.doi.org/10.1080/19336896.2020.1796898