Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death

Phosphatidylinositol 3-phosphate (PI(3)P) levels in Plasmodium falciparum correlate with tolerance to cellular stresses caused by artemisinin and environmental factors. However, PI(3)P function during the Plasmodium stress response was unknown. Here, we used PI3K inhibitors and antimalarial agents t...

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Detalles Bibliográficos
Autores principales: Lu, Kuan-Yi, Pasaje, Charisse Flerida A, Srivastava, Tamanna, Loiselle, David R, Niles, Jacquin C, Derbyshire, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518890/
https://www.ncbi.nlm.nih.gov/pubmed/32975513
http://dx.doi.org/10.7554/eLife.56773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518890/
https://www.ncbi.nlm.nih.gov/pubmed/32975513
http://dx.doi.org/10.7554/eLife.56773

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