Amiodarone’s major metabolite, desethylamiodarone inhibits proliferation of B16-F10 melanoma cells and limits lung metastasis formation in an in vivo experimental model

Previously, we demonstrated the in vitro anti-tumor effects of desethylamiodarone (DEA) in bladder and cervix cancer cell lines. In the present study, we intended to establish its potentiality in B16-F10 metastatic melanoma cells in vitro and in vivo. We assessed cell proliferation, apoptosis and ce...

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Detalles Bibliográficos
Autores principales: Bognar, Zita, Cseh, Anna Maria, Fekete, Katalin, Antus, Csenge, Bognar, Rita, Tapodi, Antal, Ramadan, Fadi H. J., Sumegi, Balazs, Gallyas, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518930/
https://www.ncbi.nlm.nih.gov/pubmed/32977329
http://dx.doi.org/10.1371/journal.pone.0239088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518930/
https://www.ncbi.nlm.nih.gov/pubmed/32977329
http://dx.doi.org/10.1371/journal.pone.0239088

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