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Engineered tissues and strategies to overcome challenges in drug development

Current preclinical studies in drug development utilize high-throughput in vitro screens to identify drug leads, followed by both in vitro and in vivo models to predict lead candidates' pharmacokinetic and pharmacodynamic properties. The goal of these studies is to reduce the number of lead dru...

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Detalles Bibliográficos
Autores principales: Khalil, Andrew S., Jaenisch, Rudolf, Mooney, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518978/
https://www.ncbi.nlm.nih.gov/pubmed/32987094
http://dx.doi.org/10.1016/j.addr.2020.09.012