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Engineered tissues and strategies to overcome challenges in drug development
Current preclinical studies in drug development utilize high-throughput in vitro screens to identify drug leads, followed by both in vitro and in vivo models to predict lead candidates' pharmacokinetic and pharmacodynamic properties. The goal of these studies is to reduce the number of lead dru...
Autores principales: | Khalil, Andrew S., Jaenisch, Rudolf, Mooney, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518978/ https://www.ncbi.nlm.nih.gov/pubmed/32987094 http://dx.doi.org/10.1016/j.addr.2020.09.012 |
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