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Sequence analysis of SARS-CoV-2 genome reveals features important for vaccine design

As the SARS-CoV-2 pandemic is rapidly progressing, the need for the development of an effective vaccine is critical. A promising approach for vaccine development is to generate, through codon pair deoptimization, an attenuated virus. This approach carries the advantage that it only requires limited...

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Detalles Bibliográficos
Autores principales: Kames, Jacob, Holcomb, David D., Kimchi, Ofer, DiCuccio, Michael, Hamasaki-Katagiri, Nobuko, Wang, Tony, Komar, Anton A., Alexaki, Aikaterini, Kimchi-Sarfaty, Chava
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519053/
https://www.ncbi.nlm.nih.gov/pubmed/32973171
http://dx.doi.org/10.1038/s41598-020-72533-2