Causal association between mTOR-dependent EIF-4E and EIF-4A circulating protein levels and type 2 diabetes: a Mendelian randomization study

The mammalian Target of Rapamycin complex 1 (mTORC1) nutrient-sensing pathway is a central regulator of cell growth and metabolism and is dysregulated in diabetes. The eukaryotic translation initiation factor 4E (EIF-4E) protein, a key regulator of gene translation and protein function, is controlle...

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Detalles Bibliográficos
Autores principales: Soliman, Ghada A., Schooling, C. Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519073/
https://www.ncbi.nlm.nih.gov/pubmed/32978410
http://dx.doi.org/10.1038/s41598-020-71987-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519073/
https://www.ncbi.nlm.nih.gov/pubmed/32978410
http://dx.doi.org/10.1038/s41598-020-71987-8

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