Polar functional group-containing glycolipid CD1d ligands modulate cytokine-biasing responses and prevent experimental colitis

The MHC class I-like molecule CD1d is a nonpolymorphic antigen-presenting glycoprotein, and its ligands include glycolipids, such as α-GalCer. The complexes between CD1d and ligands activate natural killer T cells by T cell receptor recognition, leading to the secretion of various cytokines (IFN-γ,...

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Detalles Bibliográficos
Autores principales: Inuki, Shinsuke, Hirata, Natsumi, Kashiwabara, Emi, Kishi, Junichiro, Aiba, Toshihiko, Teratani, Toshiaki, Nakamura, Wataru, Kojima, Yoshimi, Maruyama, Toru, Kanai, Takanori, Fujimoto, Yukari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519074/
https://www.ncbi.nlm.nih.gov/pubmed/32978421
http://dx.doi.org/10.1038/s41598-020-72280-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519074/
https://www.ncbi.nlm.nih.gov/pubmed/32978421
http://dx.doi.org/10.1038/s41598-020-72280-4

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