A trimeric CrRLK1L-LLG1 complex genetically modulates SUMM2-mediated autoimmunity

Cell death is intrinsically linked with immunity. Disruption of an immune-activated MAPK cascade, consisting of MEKK1, MKK1/2, and MPK4, triggers cell death and autoimmunity through the nucleotide-binding leucine-rich repeat (NLR) protein SUMM2 and the MAPK kinase kinase MEKK2. In this study, we ide...

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Detalles Bibliográficos
Autores principales: Huang, Yanyan, Yin, Chuanchun, Liu, Jun, Feng, Baomin, Ge, Dongdong, Kong, Liang, Ortiz-Morea, Fausto Andres, Richter, Julia, Hauser, Marie-Theres, Wang, Wen-Ming, Shan, Libo, He, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519094/
https://www.ncbi.nlm.nih.gov/pubmed/32978401
http://dx.doi.org/10.1038/s41467-020-18600-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519094/
https://www.ncbi.nlm.nih.gov/pubmed/32978401
http://dx.doi.org/10.1038/s41467-020-18600-8

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