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Long-term exposure to “low-dose” bisphenol A decreases mitochondrial DNA copy number, and accelerates telomere shortening in human CD8 + T cells

Exposure to the endocrine disruptor bisphenol A (BPA) has been linked with immune disorders and increased tumour risk. Our previous work in activated human peripheral blood mononuclear cells demonstrated that exposure to “low-dose” BPA diminished telomerase activity via an ER/GPR30-ERK signalling pa...

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Detalles Bibliográficos
Autores principales: Tran, Hoai Thi Thu, Herz, Corinna, Lamy, Evelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519100/
https://www.ncbi.nlm.nih.gov/pubmed/32978426
http://dx.doi.org/10.1038/s41598-020-72546-x