Intrahepatic cholangiocarcinomas with IDH1/2 mutation-associated hypermethylation at selective genes and their clinicopathological features

Intrahepatic cholangiocarcinoma (ICC) is a rare but fatal tumor. The isocitrate dehydrogenase 1 and 2 (IDH1/2) genes are known to be mutated in ICC. IDH1/2 mutations tend to be accompanied by enhanced hypermethylation at a subset of genomic loci. We sought to clarify the clinicopathological features...

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Detalles Bibliográficos
Autores principales: Lee, Kyoungbun, Song, Young Seok, Shin, Yoonju, Wen, Xianyu, Kim, Younghoon, Cho, Nam-Yun, Bae, Jeong Mo, Kang, Gyeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519101/
https://www.ncbi.nlm.nih.gov/pubmed/32978444
http://dx.doi.org/10.1038/s41598-020-72810-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519101/
https://www.ncbi.nlm.nih.gov/pubmed/32978444
http://dx.doi.org/10.1038/s41598-020-72810-0

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