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Bone morphogenetic protein 7 promotes resistance to immunotherapy

Immunotherapies revolutionized cancer treatment by harnessing the immune system to target cancer cells. However, most patients are resistant to immunotherapies and the mechanisms underlying this resistant is still poorly understood. Here, we report that overexpression of BMP7, a member of the TGFB s...

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Detalles Bibliográficos
Autores principales: Cortez, Maria Angelica, Masrorpour, Fatemeh, Ivan, Cristina, Zhang, Jie, Younes, Ahmed, Lu, Yue, Estecio, Marcos R, Barsoumian, Hampartsoum B., Menon, Hari, Caetano, Mauricio da Silva, Ramapriyan, Rishab, Schoenhals, Jonathan E., Wang, Xiaohong, Skoulidis, Ferdinandos, Wasley, Mark D., Calin, George, Hwu, Patrick, Welsh, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519103/
https://www.ncbi.nlm.nih.gov/pubmed/32973129
http://dx.doi.org/10.1038/s41467-020-18617-z