Modeling the function of BAX and BAK in early human brain development using iPSC-derived systems

Intrinsic apoptosis relies on the ability of the BCL-2 family to induce the formation of pores on the outer mitochondrial membrane. Previous studies have shown that both BAX and BAK are essential during murine embryogenesis, and reports in human cancer cell lines identified non-canonical roles for B...

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Detalles Bibliográficos
Autores principales: Joshi, Piyush, Bodnya, Caroline, Rasmussen, Megan L., Romero-Morales, Alejandra I., Bright, Anna, Gama, Vivian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519160/
https://www.ncbi.nlm.nih.gov/pubmed/32978370
http://dx.doi.org/10.1038/s41419-020-03002-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519160/
https://www.ncbi.nlm.nih.gov/pubmed/32978370
http://dx.doi.org/10.1038/s41419-020-03002-x

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