Pressure-induced amorphous zeolitic imidazole frameworks with reduced toxicity and increased tumor accumulation improves therapeutic efficacy In vivo

Zeolitic Imidazole Frameworks (ZIFs) are widely applied in nanomedicine for their high drug loading, suitable pore size, pH-responsive drug release, and so on. However, fast drug release during circulation, unexpected toxicity to mice major organs, undesirable long-term accumulation in the lung and...

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Detalles Bibliográficos
Autores principales: Jiang, Zhenqi, Li, Yanying, Wei, Zhenni, Yuan, Bo, Wang, Yinjie, Akakuru, Ozioma Udochukwu, Li, Yong, Li, Juan, Wu, Aiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519214/
https://www.ncbi.nlm.nih.gov/pubmed/33024895
http://dx.doi.org/10.1016/j.bioactmat.2020.08.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519214/
https://www.ncbi.nlm.nih.gov/pubmed/33024895
http://dx.doi.org/10.1016/j.bioactmat.2020.08.036

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