Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis

Ataxin-1 (ATXN1) is a ubiquitous polyglutamine protein expressed primarily in the nucleus where it binds chromatin and functions as a transcriptional repressor. Mutant forms of ataxin-1 containing expanded glutamine stretches cause the movement disorder spinocerebellar ataxia type 1 (SCA1) through a...

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Detalles Bibliográficos
Autores principales: Didonna, Alessandro, Canto Puig, Ester, Ma, Qin, Matsunaga, Atsuko, Ho, Brenda, Caillier, Stacy J., Shams, Hengameh, Lee, Nicholas, Hauser, Stephen L., Tan, Qiumin, Zamvil, Scott S., Oksenberg, Jorge R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519225/
https://www.ncbi.nlm.nih.gov/pubmed/32878998
http://dx.doi.org/10.1073/pnas.2003798117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519225/
https://www.ncbi.nlm.nih.gov/pubmed/32878998
http://dx.doi.org/10.1073/pnas.2003798117

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