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Synaptic secretion from human natural killer cells is diverse and includes supramolecular attack particles
Natural killer (NK) cells form immune synapses to ascertain the state of health of cells they encounter. If a target cell triggers NK cell cytotoxicity, lytic granules containing proteins including perforin and granzyme B, are secreted into the synaptic cleft inducing target cell death. Secretion of...
Autores principales: | Ambrose, Ashley R., Hazime, Khodor S., Worboys, Jonathan D., Niembro-Vivanco, Olatz, Davis, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519227/ https://www.ncbi.nlm.nih.gov/pubmed/32900953 http://dx.doi.org/10.1073/pnas.2010274117 |
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