Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation

BACKGROUND: Mitochondrial succinate accumulation has been suggested as key event for ischemia reperfusion injury in mice. No specific data are however available on behavior of liver mitochondria during ex situ machine perfusion in clinical transplant models. METHODS: We investigated mitochondrial me...

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Detalles Bibliográficos
Autores principales: Schlegel, Andrea, Muller, Xavier, Mueller, Matteo, Stepanova, Anna, Kron, Philipp, de Rougemont, Olivier, Muiesan, Paolo, Clavien, Pierre-Alain, Galkin, Alexander, Meierhofer, David, Dutkowski, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519249/
https://www.ncbi.nlm.nih.gov/pubmed/32979838
http://dx.doi.org/10.1016/j.ebiom.2020.103014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519249/
https://www.ncbi.nlm.nih.gov/pubmed/32979838
http://dx.doi.org/10.1016/j.ebiom.2020.103014

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