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Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration

BACKGROUND: During muscle regeneration, excessive formation of adipogenic and fibrogenic tissues, from their respective fibro/adipogenic progenitors (FAPs), impairs functional recovery. Intrinsic mechanisms controlling the proliferation and differentiation of FAPs remain largely unexplored. METHODS:...

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Detalles Bibliográficos
Autores principales: Zhao, Liang, Son, Jun Seok, Wang, Bo, Tian, Qiyu, Chen, Yanting, Liu, Xiangdong, de Avila, Jeanene M., Zhu, Mei-Jun, Du, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519288/
https://www.ncbi.nlm.nih.gov/pubmed/32980698
http://dx.doi.org/10.1016/j.ebiom.2020.103020