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Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling

Low-glucose and -insulin conditions, associated with ketogenic diets, can reduce the activity of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway, potentially leading to a range of positive medical and health-related effects. Here, we determined whether mTORC1 signaling is al...

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Detalles Bibliográficos
Autores principales: Warren, Eleanor C., Dooves, Stephanie, Lugarà, Eleonora, Damstra-Oddy, Joseph, Schaf, Judith, Heine, Vivi M., Walker, Mathew C., Williams, Robin S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519326/
https://www.ncbi.nlm.nih.gov/pubmed/32879008
http://dx.doi.org/10.1073/pnas.2008980117