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Records of RNA locations in living yeast revealed through covalent marks

RNA movements and localization pervade biology, from embryonic development to disease. To identify RNAs at specific locations, we developed a strategy in which a uridine-adding enzyme is anchored to subcellular sites, where it directly marks RNAs with 3′ terminal uridines. This localized RNA recordi...

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Detalles Bibliográficos
Autores principales: Medina-Munoz, Hugo C., Lapointe, Christopher P., Porter, Douglas F., Wickens, Marvin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519331/
https://www.ncbi.nlm.nih.gov/pubmed/32907940
http://dx.doi.org/10.1073/pnas.1921408117