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Secretion of pro-oncogenic AGR2 protein in cancer

Anterior gradient-2 (AGR2) protein mediates the formation, breakage and isomerization of disulphide bonds during protein maturation in the endoplasmic reticulum (ER) and contributes to the homoeostasis of the secretory pathway. AGR2 promotes tumour development and metastasis and its elevated express...

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Detalles Bibliográficos
Autores principales: Moidu, Nurshahirah Ashikin, A Rahman, Nisa Syakila, Syafruddin, Saiful Effendi, Low, Teck Yew, Mohtar, M. Aiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519367/
https://www.ncbi.nlm.nih.gov/pubmed/33005802
http://dx.doi.org/10.1016/j.heliyon.2020.e05000