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Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis

Erastin, a synthetic lethal compound against cancer expressing an oncogenic RAS, inhibits cystine/glutamate antiporters and causes ferroptosis. However, despite recent evidence for the mechanisms underlying ferroptosis, molecular biomarkers of erastin-dependent ferroptosis have not been identified....

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Detalles Bibliográficos
Autores principales: Kwon, Ok-Seon, Kwon, Eun-Ji, Kong, Hyeon-Joon, Choi, Jeong-Yoon, Kim, Yun-Jeong, Lee, Eun-Woo, Kim, Wankyu, Lee, Haeseung, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519368/
https://www.ncbi.nlm.nih.gov/pubmed/32979793
http://dx.doi.org/10.1016/j.redox.2020.101719