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Curcumin Regulates ERCC1 Expression and Enhances Oxaliplatin Sensitivity in Resistant Colorectal Cancer Cells through Its Effects on miR-409-3p

BACKGROUND: Oxaliplatin (L-OHP) resistance is a major obstacle to the effective treatment of colorectal cancer. The resistance mechanism(s) of colorectal tumors to L-OHP may be related to the regulation of ERCC1 by cancer-expressed miRNAs, but no in-depth studies on the miRNAs that affect drug resis...

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Detalles Bibliográficos
Autores principales: Han, Wei, Yin, Hongli, Ma, Hao, Wang, Yi, Kong, Desong, Fan, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519441/
https://www.ncbi.nlm.nih.gov/pubmed/33014113
http://dx.doi.org/10.1155/2020/8394574