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Making a Dent in Dent Disease
Dent disease (DD) is a rare kidney disorder caused by mutations in the Cl(−)/H(+) exchanger ClC-5. Extensive physiologic characterization of the transporter has begun to illuminate its role in endosomal ion homeostasis. Nevertheless, we have yet to understand how loss of ClC-5 function in the kidney...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519470/ https://www.ncbi.nlm.nih.gov/pubmed/33015630 http://dx.doi.org/10.1093/function/zqaa017 |