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UTX/KDM6A suppresses AP-1 and a gliogenesis program during neural differentiation of human pluripotent stem cells

BACKGROUND: UTX/KDM6A is known to interact and influence multiple different chromatin modifiers to promote an open chromatin environment to facilitate gene activation, but its molecular activities in developmental gene regulation remain unclear. RESULTS: We report that in human neural stem cells, UT...

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Detalles Bibliográficos
Autores principales: Xu, Beisi, Mulvey, Brett, Salie, Muneeb, Yang, Xiaoyang, Matsui, Yurika, Nityanandam, Anjana, Fan, Yiping, Peng, Jamy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519529/
https://www.ncbi.nlm.nih.gov/pubmed/32977832
http://dx.doi.org/10.1186/s13072-020-00359-3