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Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction

The metabolic state of an organism instructs gene expression modalities, leading to changes in complex life history traits, such as longevity. Dietary restriction (DR), which positively affects health and life span across species, leads to metabolic reprogramming that enhances utilisation of fatty a...

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Detalles Bibliográficos
Autores principales: Chamoli, Manish, Goyala, Anita, Tabrez, Syed Shamsh, Siddiqui, Atif Ahmed, Singh, Anupama, Antebi, Adam, Lithgow, Gordon J., Watts, Jennifer L., Mukhopadhyay, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519657/
https://www.ncbi.nlm.nih.gov/pubmed/32978396
http://dx.doi.org/10.1038/s41467-020-18690-4