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Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction
The metabolic state of an organism instructs gene expression modalities, leading to changes in complex life history traits, such as longevity. Dietary restriction (DR), which positively affects health and life span across species, leads to metabolic reprogramming that enhances utilisation of fatty a...
Autores principales: | Chamoli, Manish, Goyala, Anita, Tabrez, Syed Shamsh, Siddiqui, Atif Ahmed, Singh, Anupama, Antebi, Adam, Lithgow, Gordon J., Watts, Jennifer L., Mukhopadhyay, Arnab |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519657/ https://www.ncbi.nlm.nih.gov/pubmed/32978396 http://dx.doi.org/10.1038/s41467-020-18690-4 |
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