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miR-19b targets pulmonary endothelial syndecan-1 following hemorrhagic shock

Hemorrhagic shock results in systemic injury to the endothelium contributing to post-shock morbidity and mortality. The mechanism involves syndecan-1, the backbone of the endothelial glycocalyx. We have shown in a rodent model that lung syndecan-1 mRNA is reduced following hemorrhage, whereas the mo...

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Detalles Bibliográficos
Autores principales: Wu, Feng, Wang, Jian-Ying, Chao, Wei, Sims, Carrie, Kozar, Rosemary Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519668/
https://www.ncbi.nlm.nih.gov/pubmed/32978505
http://dx.doi.org/10.1038/s41598-020-73021-3