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Summary-data-based Mendelian randomization prioritizes potential druggable targets for multiple sclerosis

Multiple sclerosis is a complex autoimmune disease caused by a combination of genetic and environmental factors. Translation of Genome-Wide Association Study findings into therapeutics and effective preventive strategies has been limited to date. We used summary-data-based Mendelian randomization to...

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Detalles Bibliográficos
Autores principales: Jacobs, Benjamin M, Taylor, Thomas, Awad, Amine, Baker, David, Giovanonni, Gavin, Noyce, Alastair J, Dobson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519728/
https://www.ncbi.nlm.nih.gov/pubmed/33005893
http://dx.doi.org/10.1093/braincomms/fcaa119