Modulating Isoprenoid Biosynthesis Increases Lipooligosaccharides and Restores Acinetobacter baumannii Resistance to Host and Antibiotic Stress

Acinetobacter baumannii is a leading cause of ventilator-associated pneumonia and a critical threat due to multidrug resistance. The A. baumannii outer membrane is an asymmetric lipid bilayer composed of inner leaflet glycerophospholipids and outer leaflet lipooligosaccharides. Deleting mlaF of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Palmer, Lauren D., Minor, Keaton E., Mettlach, Joshua A., Rivera, Emilio S., Boyd, Kelli L., Caprioli, Richard M., Spraggins, Jeffrey M., Dalebroux, Zachary D., Skaar, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519801/
https://www.ncbi.nlm.nih.gov/pubmed/32905776
http://dx.doi.org/10.1016/j.celrep.2020.108129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519801/
https://www.ncbi.nlm.nih.gov/pubmed/32905776
http://dx.doi.org/10.1016/j.celrep.2020.108129

Ejemplares similares