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Modulating Isoprenoid Biosynthesis Increases Lipooligosaccharides and Restores Acinetobacter baumannii Resistance to Host and Antibiotic Stress

Acinetobacter baumannii is a leading cause of ventilator-associated pneumonia and a critical threat due to multidrug resistance. The A. baumannii outer membrane is an asymmetric lipid bilayer composed of inner leaflet glycerophospholipids and outer leaflet lipooligosaccharides. Deleting mlaF of the...

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Detalles Bibliográficos
Autores principales:	Palmer, Lauren D., Minor, Keaton E., Mettlach, Joshua A., Rivera, Emilio S., Boyd, Kelli L., Caprioli, Richard M., Spraggins, Jeffrey M., Dalebroux, Zachary D., Skaar, Eric P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519801/ https://www.ncbi.nlm.nih.gov/pubmed/32905776 http://dx.doi.org/10.1016/j.celrep.2020.108129

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