Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which motor neurons throughout the brain and spinal cord progressively degenerate resulting in muscle atrophy, paralysis and death. Recent studies using animal models of ALS implicate multiple cell-types (e.g., astrocytes and micr...

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Detalles Bibliográficos
Autores principales: Liu, Wenting, Venugopal, Sharmila, Majid, Sana, Ahn, In Sook, Diamante, Graciel, Hong, Jason, Yang, Xia, Chandler, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519882/
https://www.ncbi.nlm.nih.gov/pubmed/32360664
http://dx.doi.org/10.1016/j.nbd.2020.104877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519882/
https://www.ncbi.nlm.nih.gov/pubmed/32360664
http://dx.doi.org/10.1016/j.nbd.2020.104877

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