Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis

AIMS: Cardiovascular side effects caused by non-steroidal anti-inflammatory drugs (NSAIDs), which all inhibit cyclooxygenase (COX)-2, have prevented development of new drugs that target prostaglandins to treat inflammation and cancer. Microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors have e...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirkby, Nicholas S, Raouf, Joan, Ahmetaj-Shala, Blerina, Liu, Bin, Mazi, Sarah I, Edin, Matthew L, Chambers, Mark Geoffrey, Korotkova, Marina, Wang, Xiaomeng, Wahli, Walter, Zeldin, Darryl C, Nüsing, Rolf, Zhou, Yingbi, Jakobsson, Per-Johan, Mitchell, Jane A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519887/
https://www.ncbi.nlm.nih.gov/pubmed/31688905
http://dx.doi.org/10.1093/cvr/cvz290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519887/
https://www.ncbi.nlm.nih.gov/pubmed/31688905
http://dx.doi.org/10.1093/cvr/cvz290

Ejemplares similares