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The hybrid models, containing hydrolytic and electron-driven processes, in theoretical study of oxaliplatin biotransformation
The results of theoretical simulations of reaction paths for oxaliplatin from pro-drug into its active form responsible for cytostatic effect are presented. The studies based on the quantum-chemical density functional theory approach were performed considering environmental influence resulting from...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519906/ https://www.ncbi.nlm.nih.gov/pubmed/32979094 http://dx.doi.org/10.1007/s00894-020-04549-4 |