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Affected albumin endocytosis as a new neurotoxicity mechanism of amyloid beta
Senile plaques, a hallmark of Alzheimer's disease, are composed by Amyloid-Beta (Aβ). Aβ 25-35 toxicity is caused mainly by increasing reactive oxygen species (ROS), which is reversed by albumin preventing Aβ internalization. In addition, key cellular processes and basic cell functions require...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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AIMS Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519963/ https://www.ncbi.nlm.nih.gov/pubmed/32995492 http://dx.doi.org/10.3934/Neuroscience.2020021 |