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The Role of Prefoldin and Its Subunits in Tumors and Their Application Prospects in Nanomedicine

Prefoldin (PFDN) is a hexameric chaperone complex that is widely found in eukaryotes and archaea and consists of six different subunits (PFDN1-6). Its main function is to transfer actin and tubulin monomers to the eukaryotic cell cytoplasmic chaperone protein (c-CPN) specific binding during the asse...

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Detalles Bibliográficos
Autores principales: Mo, Shao-jian, Zhao, Hai-Chao, Tian, Yan-zhang, Zhao, Hao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520118/
https://www.ncbi.nlm.nih.gov/pubmed/33061580
http://dx.doi.org/10.2147/CMAR.S270237