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The Role of Prefoldin and Its Subunits in Tumors and Their Application Prospects in Nanomedicine
Prefoldin (PFDN) is a hexameric chaperone complex that is widely found in eukaryotes and archaea and consists of six different subunits (PFDN1-6). Its main function is to transfer actin and tubulin monomers to the eukaryotic cell cytoplasmic chaperone protein (c-CPN) specific binding during the asse...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520118/ https://www.ncbi.nlm.nih.gov/pubmed/33061580 http://dx.doi.org/10.2147/CMAR.S270237 |