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Targeting of KDM5A by miR-421 in Human Ovarian Cancer Suppresses the Progression of Ovarian Cancer Cells

PURPOSE: The retinoblastoma binding protein RBP2 (KDM5A) is a histone demethylase that promotes cell growth in many human cancers. A series of functional experiments were conducted to explore the role of miR-421/KDM5A in ovarian cancer cells and their underlying molecular mechanisms. MATERIALS AND M...

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Detalles Bibliográficos
Autores principales: Ren, Fang, Shrestha, Christina, Shi, Huirong, Sun, Fangfang, Zhang, Minghui, Cao, Yuan, Li, Gailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520141/
https://www.ncbi.nlm.nih.gov/pubmed/33061428
http://dx.doi.org/10.2147/OTT.S266211