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CaMKII‐dependent ryanodine receptor phosphorylation mediates sepsis‐induced cardiomyocyte apoptosis

Sepsis is associated with cardiac dysfunction, which is at least in part due to cardiomyocyte apoptosis. However, the underlying mechanisms are far from being understood. Using the colon ascendens stent peritonitis mouse model of sepsis (CASP), we examined the subcellular mechanisms that mediate sep...

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Detalles Bibliográficos
Autores principales: Sepúlveda, Marisa, Burgos, Juan Ignacio, Ciocci Pardo, Alejandro, González Arbelaez, Luisa, Mosca, Susana, Vila Petroff, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520277/
https://www.ncbi.nlm.nih.gov/pubmed/33460250
http://dx.doi.org/10.1111/jcmm.15470