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Knockdown of endogenous RNF4 exacerbates ischaemia‐induced cardiomyocyte apoptosis in mice

RNF4, a poly‐SUMO‐specific E3 ubiquitin ligase, is associated with protein degradation, DNA damage repair and tumour progression. However, the effect of RNF4 in cardiomyocytes remains to be explored. Here, we identified the alteration of RNF4 from ischaemic hearts and oxidative stress‐induced apopto...

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Detalles Bibliográficos
Autores principales: Qiu, Fang, Han, Yanna, Shao, Xiaoqi, Paulo, Petro, Li, Wenyue, Zhu, Mengying, Tang, Nannan, Guo, Shuaili, Chen, Yibing, Wu, Han, Zhao, Dan, Liu, Yu, Chu, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520334/
https://www.ncbi.nlm.nih.gov/pubmed/32722882
http://dx.doi.org/10.1111/jcmm.15363