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TGIF1-Twist1 axis in pancreatic ductal adenocarcinoma

TG-interacting factor 1 (TGIF1) exerts inhibitory effects on transforming growth factor-beta (TGF-β) signaling by suppressing Smad signaling pathway at multiple levels. TGIF1 activity is important for normal embryogenesis and organogenesis, yet its dysregulation can culminate in tumorigenesis. For i...

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Detalles Bibliográficos
Autores principales: Razzaque, Mohammed S., Atfi, Azeddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520386/
https://www.ncbi.nlm.nih.gov/pubmed/33005315
http://dx.doi.org/10.1016/j.csbj.2020.09.023