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Comparison of covariate selection methods with correlated covariates: prior information versus data information, or a mixture of both?
The inclusion of covariates in population models during drug development is a key step to understanding drug variability and support dosage regimen proposal, but high correlation among covariates often complicates the identification of the true covariate. We compared three covariate selection method...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520415/ https://www.ncbi.nlm.nih.gov/pubmed/32661654 http://dx.doi.org/10.1007/s10928-020-09700-5 |