Prior information for population pharmacokinetic and pharmacokinetic/pharmacodynamic analysis: overview and guidance with a focus on the NONMEM PRIOR subroutine

ABSTRACT: Population pharmacokinetic analysis is used to estimate pharmacokinetic parameters and their variability from concentration data. Due to data sparseness issues, available datasets often do not allow the estimation of all parameters of the suitable model. The PRIOR subroutine in NONMEM supp...

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Detalles Bibliográficos
Autores principales: Chan Kwong, Anna H.-X. P., Calvier, Elisa A. M., Fabre, David, Gattacceca, Florence, Khier, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520416/
https://www.ncbi.nlm.nih.gov/pubmed/32535847
http://dx.doi.org/10.1007/s10928-020-09695-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520416/
https://www.ncbi.nlm.nih.gov/pubmed/32535847
http://dx.doi.org/10.1007/s10928-020-09695-z

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