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Prefrontal inhibition of neuronal K(v)7 channels enhances prepulse inhibition of acoustic startle reflex and resistance to hypofrontality

BACKGROUND AND PURPOSE: Dysfunction of the prefrontal cortex (PFC) is involved in the cognitive deficits in neuropsychiatric diseases, such as schizophrenia, characterized by deficient neurotransmission known as NMDA receptor hypofrontality. Thus, enhancing prefrontal activity may alleviate hypofron...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Yu, Wenwen, Gao, Qin, Ju, Chuanxia, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520443/
https://www.ncbi.nlm.nih.gov/pubmed/32839968
http://dx.doi.org/10.1111/bph.15236