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Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice

The increased incidence of inflammatory bowel disease (IBD) in Western and rapidly Westernizing developing countries poses a global pandemic threat. The development of affordable drugs for treating IBD worldwide is thus a priority. Genetically modified lactic acid bacteria (gmLAB) as microbial thera...

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Detalles Bibliográficos
Autores principales: Namai, Fu, Shigemori, Suguru, Ogita, Tasuku, Sato, Takashi, Shimosato, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520878/
https://www.ncbi.nlm.nih.gov/pubmed/32989233
http://dx.doi.org/10.1038/s12276-020-00507-5