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How Monoamine Oxidase A Decomposes Serotonin: An Empirical Valence Bond Simulation of the Reactive Step

[Image: see text] The enzyme-catalyzed degradation of the biogenic amine serotonin is an essential regulatory mechanism of its level in the human organism. In particular, monoamine oxidase A (MAO A) is an important flavoenzyme involved in the metabolism of monoamine neurotransmitters. Despite extens...

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Detalles Bibliográficos
Autores principales: Prah, Alja, Purg, Miha, Stare, Jernej, Vianello, Robert, Mavri, Janez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520887/
https://www.ncbi.nlm.nih.gov/pubmed/32845149
http://dx.doi.org/10.1021/acs.jpcb.0c06502