Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

Transforming growth factor β (TGF-β) enhances migration and invasion of cancer cells, causing life-threatening metastasis. Smad7 expression is induced by TGF-β to control TGF-β signaling in a negative feedback manner. Here we report an additional function of Smad7, i.e., to enhance TGF-β induction o...

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Detalles Bibliográficos
Autores principales: Thakur, Noopur, Hamidi, Anahita, Song, Jie, Itoh, Susumu, Bergh, Anders, Heldin, Carl-Henrik, Landström, Maréne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520897/
https://www.ncbi.nlm.nih.gov/pubmed/32888405
http://dx.doi.org/10.1016/j.isci.2020.101470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520897/
https://www.ncbi.nlm.nih.gov/pubmed/32888405
http://dx.doi.org/10.1016/j.isci.2020.101470

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