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Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress

The heart manifests hypertrophic growth in response to high blood pressure, which may decompensate and progress to heart failure under persistent stress. Metabolic remodeling is an early event in this process. However, its role remains to be fully characterized. Here, we show that lactate dehydrogen...

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Detalles Bibliográficos
Autores principales: Dai, Chongshan, Li, Qinfeng, May, Herman I., Li, Chao, Zhang, Guangyu, Sharma, Gaurav, Sherry, A. Dean, Malloy, Craig R., Khemtong, Chalermchai, Zhang, Yuannyu, Deng, Yingfeng, Gillette, Thomas G., Xu, Jian, Scadden, David T., Wang, Zhao V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520916/
https://www.ncbi.nlm.nih.gov/pubmed/32877669
http://dx.doi.org/10.1016/j.celrep.2020.108087